So, my subject pretty much says it all. This was one of those cases where the anime did a better job than the original and the voices/sound were spot on and truly aided in making it funnier. I read through the manga after going through the anime and found the manga to be less funny, to the point where I started to search after and only read chapters or parts that were skipped in the anime, which honestly wasn't much. Sadly, even those pages rarely made me laugh, it just wasn't as good without the wacky voices and animations.
Now, it's not bad even so, I just recommend the anime over the manga. It's a great manga with a lot of jokes, being truly hilarious at times. Thanks to the versatility of the ESP, we get a lot of different situations and it doesn't feel too repetitive unlike many other comedy manga. Well, after 200+ chapters, I honestly felt like I was starting to get a bit bored, I recommend spreading this out a bit more and not read it in one or two sittings. Maybe you could even spread it out between manga and read some other manga after reading a few dozen chapters of this manga before coming back to read a few dozen more.
This story is pretty much the story of saiki, the all-powerful, god-like esp user that has too OP powers which interferes with his daily life and causes many issues, especially since there's no "off" button for many of them. This in turn causes many different situations where he's being bothered and has to deal with stuff related to the powers, from holding conversations with cocky animals to trying to control his powers so that he doesn't accidentally kill someone or blow away half the city and everything inbetween. He has a pretty cynical attitude and thinks of everything as a bother, although it doesn't stop him from helping people and trying to do stuff.
Honestly, I held off on reading this for quite a long time because... Seriously, let's be honest here, he looks retarded with the balls on his head and green glasses along with dead eyes. I kind of assumed it was some stupid crap made for young teens or kids thanks to these things, well, it just didn't give me a good first impression. I couldn't have been more wrong, so if you're like me and judged it by its cover, give it a few chapters, it's certainly not that childish and stupid.