The first chapter might put you off a bit, since the drawings are pretty ugly and the nose hair thing is repulsive, but if you stick with it just a bit, you'll see why many people absolutely love this Manga.
The manga seems to essentially follow the typical shonen route, with fights, evil villains, pretty girl side kicks, etc. - all the stuff you find in your generic boy adventures, except everything is turned upside down.
In particular, it is very interesting to see some of the focus on manzai (a Japanese form of comedy), which is surprisingly well suited for combat in manga parody form. Seriously: the wins from comedic super powers don't seem any less believable that what you get from Bleach or whatever, but the extra layers on top with all the comedic and absurd tangents make bobobo a real gem.
Bobobo is easy to read, but rich in detail and thought.
... and to the Headache below, offering reviews of the anime: this is a site for reviewing manga. Thanks.